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Understanding Long-term Respiratory Morbidity in Former Styrene-exposed Workers: Medical Survey

Information session presentation

OMB: 0920-1332

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Understanding Long-term Respiratory Morbidity Among Former Styrene-Exposed Workers: Medical Survey


Suzanne Tomasi, DVM, MPH, DACVPM

Epidemiologist
Field Studies Branch

Respiratory Health Division

Month XX, 2020

 

Objectives

  • Review previous industrial hygiene and mortalities studies from boatbuilders exposed to styrene 

  • Review the known health effects from styrene exposure 

  • Introduce a new NIOSH study involving workers with previous
    styrene exposure 

 

Who is NIOSH?

  • National Institute for Occupational Safety and Health (NIOSH) is a federal public health agency and is a part of the Centers for Disease Control and Prevention (CDC)  

  • NIOSH is responsible for conducting research and making recommendations for the prevention of work-related illnesses and injuries 

  • NIOSH is not part of the Occupational Safety and Health Administration (OSHA) and does not enforce workplace health and safety laws 

 

Why has NIOSH invited me?

  • You worked at either Uniflite or Tollycraft during 1959 and 1978 

  • You are part of the NIOSH boatbuilder cohort 

 

What is styrene?

  • Synthetic chemical used in the manufacturing of reinforced plastics and synthetic rubbers 

  • In 2008, over 12 billion pounds of styrene were produced in the U.S. 

  • 90,000 workers are exposed to styrene at 5,000 U.S. manufacturing plants 

 

  • NIOSH recommended exposure limit is 50 parts per million  

 

How are workers exposed to styrene?

  • Inhalation 

  • Skin absorption 

  • Ingestion 

 

What are known health effects of styrene exposure?

  • Color vision changes 

  • Hearing loss 

  • Cognitive impairment 

  • Cancer 

  • Non-malignant respiratory diseases 

 

What have previous studies told us?

  • Mortality analyses for a boatbuilder cohort of 5,204 workers 

    • 2,063 had high styrene exposure 

    • 3,141 had minimal styrene exposure 

    • Individuals who worked in Fibrous glass or Lamination department
      had high styrene exposure 

    • Mean 8-hour styrene concentrations for all high-exposure jobs in
      the two plants were 42.5 and 71.7 parts per million  

    • High styrene-exposed workers had two times higher death rate from COPD compared with general population 

 

What have previous studies told us?

  • Analyzed 157 decedents from the boatbuilder cohort 

    • Investigated workers who died at age <55 years 

    • Identified one worker who died from bronchiolitis in early 30’s  

    • Identified nine workers who died from COPD at age <55 years 

  • Published a paper that identified multiple cases of respiratory
    disease among styrene-exposed workers 

 

What’s next?

  • Conducting a research study to understand the long-term respiratory health effects among styrene-exposed workers 

  • Developing effective prevention strategies for current and future
    styrene-exposed workers 

 

What will I be asked to do if I participate?

  • Questionnaire 

  • Color Vision Test 

  • Blood Test 

  • Breathing tests 

 

When, where, for how long will you need me?

  • Month XX, 20XX or Month XX, 20XX 

  • Location 

  • Two and a half hours 

 

What are the benefits?

  • Results beneficial to current and future styrene-exposed workers 

Will I be reimbursed or paid?

  • $50 gift card  

 

What are the risks?

  • Discomfort due to medical tests 

  • Recommendations for further medical tests by your personal
    healthcare provider  

  • Unintentional disclosure of personal identifiable information 

 

What precautions will NIOSH take to minimize risks?

  • Confirm participants’ contradiction to any medical procedures 

  • Use trained phlebotomists for blood draw 

  • Provide list of free and income-based clinics 

  • Store personal identifiable information securely 

 

Is my participation voluntary?

  • Your participation is voluntary 

  • You may participate in some or all study procedures offered 

  • You may drop out of the study at any time without penalty 

 



What will happen with the results of the study?

  • Present study findings  

    • Boat builder cohorts 

    • Labor unions 

    • Scientific research communities 

  • Develop effective prevention strategies for current and future
    styrene-exposed workers 

 


Will my personal information be kept private?

  • Certificate of Confidentiality 

  • Not reveal information without consent 

  • Store personal identifiable information securely 

 

You have the opportunity to directly ask us the questions about the study and your participation

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