Pilot Testing on New NHANES 2009-10 Content

Attachment I.

Protocol for Chemosensory Variation and Impairment Pilot Study (ages 40+)

National Health and Nutrition Examination Survey (NHANES)

Chemosensory Variation and Impairment Pilot Study

OMB no. 0920-0237

Expires: 12/31/2011

Assurance of confidentiality – All information which would permit identification of an

individual, a practice, or an establishment will be held confidential, will be used for

statistical purposes only by NCHS staff, contractors, and agents only when required and with necessary controls, and will not be disclosed or released to other persons without the consent of the individual or establishment in accordance with section 308(d) of the Public Health Service Act (42 USC 242m) and the Confidential Information Protection and Statistical Efficiency Act (PL-107-347).

Public reporting burden of this collection of information is estimated to average 10 minutes per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. An agency may not conduct or sponsor, and a person is not required to respond to a collection of information unless it displays a currently valid OMB control number. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to CDC/ATSDR Reports Clearance Officer; 1600 Clifton Road, MS D-74, Atlanta, GA 30333. ATTN: PRA (0920-0237).

Chemosensory Variation and Impairment Pilot Study Protocol:

Eligibility: Sample persons aged 40 years or older are eligible for the Chemosensory Variation and Impairment Pilot Study.

Informed Consent: Informed consent will be obtained as a part of standard NHANES consenting procedures.

Exclusion Criteria: Persons cognitively impaired or who feel unable to perform testing because of hypersensitivity to specific tastes or smells will be excluded.

Study Design: Smell testing will be performed using the Brief Smell Identification Test (BSIT- also known as the CC-SIT) which is a well standardized "scratch and sniff" smell identification test. Taste testing will be performed by having the examinee taste a small amount of a test substance (sweet, sour, bitter, salty, etc) to determine if they can correctly identify the taste. A nose clip will be used to eliminate the possibility of the examinee smelling the substance during the taste test. If the examinee is hypersensitive to bitter taste, a sugar mouth rinse will be available to immediately quench the taste.

Data Collection: The data will be collected in the Mobile Examination Center (MEC).

Report of Findings: Results will not be reported to the participant.