CARDIOVASCULAR HEALTH STUDY TIMELINE
Population: A total of 5,201 men and women aged 65+ (approximately 1,300 in each of four communities) recruited at baseline, and an additional 687 African-Americans (approximately 230 in each of three of the communities) recruited at the third follow-up examination.
Study Year Calendar Year Activity
1 1988-89 Write protocol and pilot test
2 1989-90 Baseline Examination to assess:
Risk factors
Medical history (CHD, stroke, related diagnoses,
medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Carotid ultrasonography
Hemostasis: coagulation, fibrinolysis
Lipids, lipoproteins
Fasting blood insulin, glucose, chemistries, (stored
blood)
Glucose tolerance test
Hematology: hematocrit, WBC, platelet count
Echocardiography
Electrocardiogram (resting and ambulatory)
Pulmonary function testing
Education, smoking, physical activity
Physical function testing
3-4 1990-92 Surveillance contacts with study participants at 6- month intervals (three phone contacts, two brief clinic or home interviews)
5 1992-93 Follow-up examination
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke, related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Carotid ultrasonography
Hemostasis: coagulation, fibrinolysis
Lipids, lipoproteins
Fasting blood insulin, glucose, chemistries
(stored blood)
Hemotology: Hematocrit, WBC
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
New Components:
Cerebral magnetic resonance imaging (MRI), first half of cohort
Aortic ultrasonography
Hospital records
Death certificates and investigations for cause of death
6 1993-4 Surveillance Contacts with study participants at 6-month intervals (one phone contact, one clinical examination)
Repeat baseline components:
Risk Factors
Interim medical history (CHD, Stroke, related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Cholesterol
Electrocardiogram (resting and ambulatory)
Education, smoking physical activity
Physical function testing
Pulmonary function testing
New components:
Cerebral magnetic resonance imaging (MRI), second half cohort
Peak-flow testing
Oximetry
Hospital records
Death certificates and investigations for cause of death
7 1994-5 Surveillance Contacts with study participants at 6-month intervals (one phone contact, one clinic examination)
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke, related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Cholesterol
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
Echocardiography
First half of cohort
Ambulatory electrocardiography
Repeat on one-third of cohort
New component
Bone Density
Hospital records
Death certificates and investigations for cause of death
8 1995-6 8 1995-96 Surveillance Contacts with study participants at 6-
month intervals (one phone contact, one clinic
examination)
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke, related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Cholesterol
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
Nutrition
Echocardiography
Second half of cohort
Hospital records
Death certificates and investigations for cause of death
9 1996-7 Surveillance Contacts with study participants at 6-
month intervals (one phone contact, one clinic
examination)
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke, related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Cholesterol
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
Physical activity
Hemostasis: coagulation, fibrinolysis
Lipids, lipoproteins
Fasting blood insulin, glucose, chemistries
Hematology: Hematocrit, WBC
Supine Ankle-Arm Blood Pressure
Carotid and Aortic Ultrasound
Ambulatory electrocardiography
repeat on one-third of cohort
Hospital records
Death certificates and investigation for
cause of death
10 1997-8 Surveillance Contacts with study participants at 6 month intervals (two phone contact, one clinic examination)
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke,
related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight, distribution of body fat
Cholesterol
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
Orthostatic Blood Pressure
Pulmonary function testing
Cerebral MRI (first half of cohort)
Spot Urine Collection
Hospital records
Death certificates and investigations for
cause of death
11 1198-9 Surveillance Contacts with study participant at 6-
month intervals (two phone contacts, one clinic examination)
Repeat baseline components:
Risk factors
Interim medical history (CHD, stroke,
related diagnoses, medical care, medications)
Physical examination
Blood pressure, pulse, postural changes
Height, weight
Cholesterol
Hemostasis: coagulation, fibrinolysis
Lipids, lipoproteins
Fasting blood insulin, glucose, chemistries
Hematology: Hematocrit, WBC
Supine Ankle-Arm Blood Pressure
Electrocardiogram (resting and ambulatory)
Education, smoking, physical activity
Physical function testing
Carotid and Aortic Ultrasound
Cerebral MRI (second half of cohort)
Retinal photography
Six-minute walk with oximetry
Hearing Test
Hemodynamic Reactivity
Trails A & B
Grooved Pegboard
Hospital records
Death certificates and investigation for
cause of death
12-19* 1999-2008 Surveillance Contacts with study participants at 6-
month intervals (semi-annual phone contacts)
Hospital records
Death certificates and investigations for cause of
death analyses
* For Years 18-19 (2007-2008), surveillance contacts are conducted under the CHS contract only at the Pittsburgh site; surveillance contacts at other sites are supported by investigator-initiated grant funding.
| File Type | application/msword |
| File Title | Table 7-A |
| Author | OlsonJ |
| Last Modified By | olsonj |
| File Modified | 2007-10-30 |
| File Created | 2007-10-30 |