This survey is to identify female,
reproductive aged twin pairs in which both co-twins are living and
at least one co-twin is likely to have PCOS. Twins meeting the
study criteria will be used as a resoruce for future studies aimed
at identifying the environmental factors important to PCOS
development. The Mid-Atlantic Twin Registry will administer the
survey which was designed to be simple, direct, and easily
completed in 10 minutes. Questions involve period irregularity and
evidence of hyperandrogenism. The subjects will also be asked about
their willingness to participate in furture PCOS studies.
On behalf of this Federal agency, I certify that
the collection of information encompassed by this request complies
with 5 CFR 1320.9 and the related provisions of 5 CFR
1320.8(b)(3).
The following is a summary of the topics, regarding
the proposed collection of information, that the certification
covers:
(i) Why the information is being collected;
(ii) Use of information;
(iii) Burden estimate;
(iv) Nature of response (voluntary, required for a
benefit, or mandatory);
(v) Nature and extent of confidentiality; and
(vi) Need to display currently valid OMB control
number;
If you are unable to certify compliance with any of
these provisions, identify the item by leaving the box unchecked
and explain the reason in the Supporting Statement.